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Sphingosine 1-Phosphate Receptor 4 Promotes Nonalcoholic Steatohepatitis by Activating NLRP3 Inflammasome

BACKGROUND & AIMS: Sphingosine 1-phosphate receptors (S1PRs) are a group of G-protein–coupled receptors that confer a broad range of functional effects in chronic inflammatory and metabolic diseases. S1PRs also may mediate the development of nonalcoholic steatohepatitis (NASH), but the specific...

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Detalles Bibliográficos
Autores principales:	Hong, Chung Hwan, Ko, Myoung Seok, Kim, Jae Hyun, Cho, Hyunkyung, Lee, Chi-Ho, Yoon, Ji Eun, Yun, Ji-Young, Baek, In-Jeoung, Jang, Jung Eun, Lee, Seung Eun, Cho, Yun Kyung, Baek, Ji Yeon, Oh, Soo Jin, Lee, Bong Yong, Lim, Joon Seo, Lee, Jongkook, Hartig, Sean M., Conde de la Rosa, Laura, Garcia-Ruiz, Carmen, Lee, Ki-Up, Fernández-Checa, Jose C., Choi, Ji Woong, Kim, Sanghee, Koh, Eun Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810559/ https://www.ncbi.nlm.nih.gov/pubmed/34890841 http://dx.doi.org/10.1016/j.jcmgh.2021.12.002

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