CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing

OBJECTIVE: Enhanced de novo lipogenesis (DNL) in hepatocytes is a major contributor to nonalcoholic fatty liver disease (NAFLD). Fatty acid translocase (FAT/CD36) is involved in the pathogenesis of NAFLD through facilitating free fatty acids uptake. Here, we explored the effects of CD36 on DNL and e...

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Detalles Bibliográficos
Autores principales: Zeng, Han, Qin, Hong, Liao, Meng, Zheng, Enze, Luo, Xiaoqing, Xiao, Anhua, Li, Yiyu, Chen, Lin, Wei, Li, Zhao, Lei, Ruan, Xiong Z., Yang, Ping, Chen, Yaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810570/
https://www.ncbi.nlm.nih.gov/pubmed/34974159
http://dx.doi.org/10.1016/j.molmet.2021.101428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810570/
https://www.ncbi.nlm.nih.gov/pubmed/34974159
http://dx.doi.org/10.1016/j.molmet.2021.101428

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