Engineered bacterial voltage-gated sodium channel platform for cardiac gene therapy

Therapies for cardiac arrhythmias could greatly benefit from approaches to enhance electrical excitability and action potential conduction in the heart by stably overexpressing mammalian voltage-gated sodium channels. However, the large size of these channels precludes their incorporation into thera...

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Detalles Bibliográficos
Autores principales: Nguyen, Hung X., Wu, Tianyu, Needs, Daniel, Zhang, Hengtao, Perelli, Robin M., DeLuca, Sophia, Yang, Rachel, Pan, Michael, Landstrom, Andrew P., Henriquez, Craig, Bursac, Nenad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810800/
https://www.ncbi.nlm.nih.gov/pubmed/35110560
http://dx.doi.org/10.1038/s41467-022-28251-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810800/
https://www.ncbi.nlm.nih.gov/pubmed/35110560
http://dx.doi.org/10.1038/s41467-022-28251-6

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