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Engineered bacterial voltage-gated sodium channel platform for cardiac gene therapy
Therapies for cardiac arrhythmias could greatly benefit from approaches to enhance electrical excitability and action potential conduction in the heart by stably overexpressing mammalian voltage-gated sodium channels. However, the large size of these channels precludes their incorporation into thera...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810800/ https://www.ncbi.nlm.nih.gov/pubmed/35110560 http://dx.doi.org/10.1038/s41467-022-28251-6 |