Cargando…

Immune Checkpoint Gene Expression Profiling Identifies Programmed Cell Death Ligand-1 Centered Immunologic Subtypes of Oral and Squamous Cell Carcinoma With Favorable Survival

OBJECTIVE: This study aimed to identify the programmed death ligand-1 (PDL1, also termed as CD274) and its positively correlated immune checkpoint genes (ICGs) and to determine the immune subtypes of CD274-centered ICG combinations in oral and squamous cell carcinoma (OSCC). MATERIALS AND METHODS: F...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Yang, Tang, Huiwen, Franceschi, Debora, Mujagond, Prabhakar, Acharya, Aneesha, Deng, Yupei, Lethaus, Bernd, Savkovic, Vuk, Zimmerer, Rüdiger, Ziebolz, Dirk, Li, Simin, Schmalz, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810827/ https://www.ncbi.nlm.nih.gov/pubmed/35127742 http://dx.doi.org/10.3389/fmed.2021.759605

Ejemplares similares

Molecular Subtypes of Oral Squamous Cell Carcinoma Based on Immunosuppression Genes Using a Deep Learning Approach
por: Li, Simin, et al.
Publicado: (2021)

Single-Cell Transcriptome Analysis Reveals Different Immune Signatures in HPV- and HPV + Driven Human Head and Neck Squamous Cell Carcinoma
por: Li, Simin, et al.
Publicado: (2022)

Identifying crosstalk genetic biomarkers linking a neurodegenerative disease, Parkinson’s disease, and periodontitis using integrated bioinformatics analyses
por: Hu, Shaonan, et al.
Publicado: (2022)

Identification of miRNAs as the Crosstalk in the Interaction between Neural Stem/Progenitor Cells and Endothelial Cells
por: Wang, Xin, et al.
Publicado: (2020)

Shared Genetic and Epigenetic Mechanisms between the Osteogenic Differentiation of Dental Pulp Stem Cells and Bone Marrow Stem Cells
por: Gaus, Sebastian, et al.
Publicado: (2021)

Evaluation of an individual anamnesis tool for teaching risk-oriented prevention – a pilot study in undergraduate dental students
por: Schmalz, Gerhard, et al.
Publicado: (2022)

The Angiogenic Potential of Mesenchymal Stem Cells from the Hair Follicle Outer Root Sheath
por: Savkovic, Vuk, et al.
Publicado: (2021)

Shared Molecular Mechanisms between Atherosclerosis and Periodontitis by Analyzing the Transcriptomic Alterations of Peripheral Blood Monocytes
por: Ning, Wanchen, et al.
Publicado: (2021)

Oral Health Screening for Risk Reduction for Early Periprosthetic Joint Infections of Hip and Knee Endoprostheses—Results of a Prospective Cohort Study
por: Fenske, Fabian, et al.
Publicado: (2023)

The Middle Part of the Plucked Hair Follicle Outer Root Sheath Is Identified as an Area Rich in Lineage-Specific Stem Cell Markers
por: Li, Hanluo, et al.
Publicado: (2021)

Osteogenic Potential of Mesenchymal Stem Cells from Adipose Tissue, Bone Marrow and Hair Follicle Outer Root Sheath in a 3D Crosslinked Gelatin-Based Hydrogel
por: Li, Hanluo, et al.
Publicado: (2021)

Molecular mechanisms linking peri-implantitis and type 2 diabetes mellitus revealed by transcriptomic analysis
por: Yu, Tianliang, et al.
Publicado: (2019)

Oral Health-Related Quality of Life in Patients With Chronic Respiratory Diseases—Results of a Systematic Review
por: Li, Simin, et al.
Publicado: (2022)

Mesenchymal Stem Cells Isolated from Equine Hair Follicles Using a Method of Air-Liquid Interface
por: Li, Hanluo, et al.
Publicado: (2023)

Identification of Key Pyroptosis-Related Genes and Distinct Pyroptosis-Related Clusters in Periodontitis
por: Ning, Wanchen, et al.
Publicado: (2022)

Oral Health-Related Quality of Life in Patients after Stroke—A Systematic Review
por: Schmalz, Gerhard, et al.
Publicado: (2022)

Deep Learning Reveals Key Immunosuppression Genes and Distinct Immunotypes in Periodontitis
por: Ning, Wanchen, et al.
Publicado: (2021)

Shared Molecular Mechanisms between Alzheimer's Disease and Periodontitis Revealed by Transcriptomic Analysis
por: Jin, Jieqi, et al.
Publicado: (2021)

Integration of the Tumor Mutational Burden and Tumor Heterogeneity Identify an Immunological Subtype of Melanoma With Favorable Survival
por: Gao, Yanmei, et al.
Publicado: (2020)

Transcriptomic analysis reveals pathophysiological relationship between chronic obstructive pulmonary disease (COPD) and periodontitis
por: Liu, Shuqin, et al.
Publicado: (2022)

No Significant Bone Resorption after Open Treatment of Mandibular Condylar Head Fractures in the Medium-Term
por: Neuhaus, Michael-Tobias, et al.
Publicado: (2022)

Congenital Mandibular Hypoplasia: Patient-Specific Total Joint Replacement as a Line Extension in the Treatment of Complex Craniofacial Anomalies
por: Zimmerer, Rüdiger M., et al.
Publicado: (2022)

Super-Enhancer-Associated Long Non-Coding RNA LINC01485 Promotes Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Regulating MiR-619-5p/RUNX2 Axis
por: Gu, Wenli, et al.
Publicado: (2022)

Special Issue “Oral Health and Systemic Diseases”
por: Schmalz, Gerhard, et al.
Publicado: (2020)

Changing the Focus to the Whole Patient instead of One Oral Disease: The Concept of Individualized Prevention
por: Schmalz, Gerhard, et al.
Publicado: (2020)

Eyes wide shut: necessity and effect of adjunctive procedures after decompression surgery in patients with endocrine orbitopathy
por: Krause, Matthias, et al.
Publicado: (2021)

Accuracy of Guided Surgery and Real-Time Navigation in Temporomandibular Joint Replacement Surgery
por: Neuhaus, Michael-Tobias, et al.
Publicado: (2021)

Continuous Multidisciplinary Care for Patients With Orofacial Clefts—Should the Follow-up Interval Depend on the Cleft Entity?
por: Sander, Anna K., et al.
Publicado: (2021)

MicroRNAs as Salivary Markers for Periodontal Diseases: A New Diagnostic Approach?
por: Schmalz, Gerhard, et al.
Publicado: (2016)

Oral health and oral health-related quality of life in patients with oral dystonia indicates their need for dental special care
por: Schmalz, Gerhard, et al.
Publicado: (2021)

Consideration of specific key points improves outcome of decompression treatment in patients with endocrine orbitopathy: pre-/post-OP comparison and biomechanical simulation
por: Krause, Matthias, et al.
Publicado: (2022)

Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
por: Li, Hanluo, et al.
Publicado: (2022)

Clinical Follow-Up in Orofacial Clefts—Why Multidisciplinary Care Is the Key
por: Lethaus, Bernd, et al.
Publicado: (2021)

Identification of immunologic subtype and prognosis of GBM based on TNFSF14 and immune checkpoint gene expression profiling
por: Long, Shengrong, et al.
Publicado: (2020)

Autologous, Non-Invasively Available Mesenchymal Stem Cells from the Outer Root Sheath of Hair Follicle Are Obtainable by Migration from Plucked Hair Follicles and Expandable in Scalable Amounts
por: Li, Hanluo, et al.
Publicado: (2020)

Accuracy of low-cost alternative facial scanners: a prospective cohort study
por: Bartella, Alexander K., et al.
Publicado: (2022)

Oral health-related quality of life in adult patients with end-stage kidney diseases undergoing renal replacement therapy – a systematic review
por: Schmalz, Gerhard, et al.
Publicado: (2020)

Oral-Health-Related Quality of Life in Adult Patients with Rheumatic Diseases—A Systematic Review
por: Schmalz, Gerhard, et al.
Publicado: (2020)

Does oral health-related quality of life of patients after solid organ transplantation indicate a response shift? Results of a systematic review
por: Schmalz, Gerhard, et al.
Publicado: (2020)

Oral hygiene and oral health behavior, periodontal complaints and oral health-related quality of life in pregnant women
por: Schröter, Uwe, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_efv6ihf2dmnqrq89sdvvh1i6op