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Inhibition of Orai Channel Function Regulates Mas-Related G Protein-Coupled Receptor-Mediated Responses in Mast Cells

Mast cells (MCs) are tissue resident immune cells that play important roles in the pathogenesis of allergic disorders. These responses are mediated via the cross-linking of cell surface high affinity IgE receptor (FcϵRI) by antigen resulting in calcium (Ca(2+)) mobilization, followed by degranulatio...

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Detalles Bibliográficos
Autores principales:	Chaki, Shaswati, Alkanfari, Ibrahim, Roy, Saptarshi, Amponnawarat, Aetas, Hui, Yvonne, Oskeritzian, Carole A., Ali, Hydar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810828/ https://www.ncbi.nlm.nih.gov/pubmed/35126366 http://dx.doi.org/10.3389/fimmu.2021.803335

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