Mesencephalic astrocyte-derived neurotrophic factor reprograms macrophages to ameliorate acetaminophen-induced acute liver injury via p38 MAPK pathway

Acetaminophen (APAP)-induced liver injury (AILI) is the most frequent cause of acute liver failure; but the underlying mechanisms still remain obscure. Macrophages and endoplasmic reticulum (ER) stress play an important role in the pathogenesis of AILI. Mesencephalic astrocyte-derived neurotrophic f...

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Detalles Bibliográficos
Autores principales: Hou, Xin, Liu, Qi, Gao, Yimin, Yong, Liang, Xie, Huiyuan, Li, Wenting, Zhou, Yuping, Liu, Jun, Feng, Lijie, Xu, Long, Shen, Yuxian, Wang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8810950/
https://www.ncbi.nlm.nih.gov/pubmed/35110525
http://dx.doi.org/10.1038/s41419-022-04555-9

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