LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy

Long non-coding RNAs (lncRNAs) play critical functions in various cancers. Firre intergenic repeating RNA element (FIRRE), a lncRNA located in the nucleus, was overexpressed in colorectal cancer (CRC). However, the detailed mechanism of FIRRE in CRC remains elusive. Results of RNA sequence and qPCR...

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Detalles Bibliográficos
Autores principales: Wang, Yajie, Li, Zhengyang, Xu, Shizan, Li, Wenjun, Chen, Mengyun, Jiang, Miao, Fan, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811066/
https://www.ncbi.nlm.nih.gov/pubmed/35110535
http://dx.doi.org/10.1038/s41419-022-04509-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811066/
https://www.ncbi.nlm.nih.gov/pubmed/35110535
http://dx.doi.org/10.1038/s41419-022-04509-1

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