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LncRNA FIRRE functions as a tumor promoter by interaction with PTBP1 to stabilize BECN1 mRNA and facilitate autophagy
Long non-coding RNAs (lncRNAs) play critical functions in various cancers. Firre intergenic repeating RNA element (FIRRE), a lncRNA located in the nucleus, was overexpressed in colorectal cancer (CRC). However, the detailed mechanism of FIRRE in CRC remains elusive. Results of RNA sequence and qPCR...
Autores principales: | Wang, Yajie, Li, Zhengyang, Xu, Shizan, Li, Wenjun, Chen, Mengyun, Jiang, Miao, Fan, Xiaoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811066/ https://www.ncbi.nlm.nih.gov/pubmed/35110535 http://dx.doi.org/10.1038/s41419-022-04509-1 |
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