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Mesenchymal stromal cell-derived small extracellular vesicles promote neurological recovery and brain remodeling after distal middle cerebral artery occlusion in aged rats
Small extracellular vesicles (sEVs) obtained from mesenchymal stromal cells (MSCs) promote neurological recovery after middle cerebral artery occlusion (MCAO) in young rodents. Ischemic stroke mainly affects aged humans. MSC-sEV effects on stroke recovery in aged rodents had not been assessed. In a...
Autores principales: | Dumbrava, Danut-Adrian, Surugiu, Roxana, Börger, Verena, Ruscu, Mihai, Tertel, Tobias, Giebel, Bernd, Hermann, Dirk M., Popa-Wagner, Aurel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811093/ https://www.ncbi.nlm.nih.gov/pubmed/34757568 http://dx.doi.org/10.1007/s11357-021-00483-2 |
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