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Effect of Sophocarpine on the Pharmacokinetics of Umbralisib in Rat Plasma Using a Novel UPLC-MS/MS Method

Umbralisib is a dual inhibitor of phosphatidylinositol 3-kinase delta (PI3Kδ) and casein kinase 1 epsilon (CK1ε) for treating marginal zone lymphoma (MZL) and follicular lymphoma (FL). This study aimed to develop a fast and stable ultra performance liquid chromatography tandem mass spectrometry (UPL...

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Detalles Bibliográficos
Autores principales:	Weng, Qinghua, Lan, Xia, Wang, Yingjie, Fan, Chen, Xu, Ren-ai, Zhang, Pengzhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811118/ https://www.ncbi.nlm.nih.gov/pubmed/35126158 http://dx.doi.org/10.3389/fphar.2022.749095

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