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Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains
The pathogenic microorganism Listeria monocytogenes is ubiquitous and responsible for listeriosis, a disease with a high mortality rate in susceptible people. It can persist in different habitats, including the farm environment, the food production environments, and in foods. This pathogen can grow...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811131/ https://www.ncbi.nlm.nih.gov/pubmed/35126322 http://dx.doi.org/10.3389/fmicb.2021.738470 |
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author | Lakicevic, Brankica Z. Den Besten, Heidy M. W. De Biase, Daniela |
author_facet | Lakicevic, Brankica Z. Den Besten, Heidy M. W. De Biase, Daniela |
author_sort | Lakicevic, Brankica Z. |
collection | PubMed |
description | The pathogenic microorganism Listeria monocytogenes is ubiquitous and responsible for listeriosis, a disease with a high mortality rate in susceptible people. It can persist in different habitats, including the farm environment, the food production environments, and in foods. This pathogen can grow under challenging conditions, such as low pH, low temperatures, and high salt concentrations. However, L. monocytogenes has a high degree of strain divergence regarding virulence potential, environmental adaption, and stress response. This review seeks to provide the reader with an up-to-date overview of clonal and serotype-specific differences among L. monocytogenes strains. Emphasis on the genes and genomic islands responsible for virulence and resistance to environmental stresses is given to explain the complex adaptation among L. monocytogenes strains. Moreover, we highlight the use of advanced diagnostic technologies, such as whole-genome sequencing, to fine-tune quantitative microbiological risk assessment for better control of listeriosis. |
format | Online Article Text |
id | pubmed-8811131 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88111312022-02-04 Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains Lakicevic, Brankica Z. Den Besten, Heidy M. W. De Biase, Daniela Front Microbiol Microbiology The pathogenic microorganism Listeria monocytogenes is ubiquitous and responsible for listeriosis, a disease with a high mortality rate in susceptible people. It can persist in different habitats, including the farm environment, the food production environments, and in foods. This pathogen can grow under challenging conditions, such as low pH, low temperatures, and high salt concentrations. However, L. monocytogenes has a high degree of strain divergence regarding virulence potential, environmental adaption, and stress response. This review seeks to provide the reader with an up-to-date overview of clonal and serotype-specific differences among L. monocytogenes strains. Emphasis on the genes and genomic islands responsible for virulence and resistance to environmental stresses is given to explain the complex adaptation among L. monocytogenes strains. Moreover, we highlight the use of advanced diagnostic technologies, such as whole-genome sequencing, to fine-tune quantitative microbiological risk assessment for better control of listeriosis. Frontiers Media S.A. 2022-01-20 /pmc/articles/PMC8811131/ /pubmed/35126322 http://dx.doi.org/10.3389/fmicb.2021.738470 Text en Copyright © 2022 Lakicevic, Den Besten and De Biase. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Microbiology Lakicevic, Brankica Z. Den Besten, Heidy M. W. De Biase, Daniela Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains |
title | Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains |
title_full | Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains |
title_fullStr | Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains |
title_full_unstemmed | Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains |
title_short | Landscape of Stress Response and Virulence Genes Among Listeria monocytogenes Strains |
title_sort | landscape of stress response and virulence genes among listeria monocytogenes strains |
topic | Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811131/ https://www.ncbi.nlm.nih.gov/pubmed/35126322 http://dx.doi.org/10.3389/fmicb.2021.738470 |
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