An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

BACKGROUNDS & AIMS: Primary biliary cholangitis (PBC) is a chronic liver disease in which autoimmune destruction of the small intrahepatic bile ducts eventually leads to cirrhosis. Many patients have inadequate response to licensed medications, motivating the search for novel therapies. Previous...

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Detalles Bibliográficos
Autores principales: Cordell, Heather J., Fryett, James J., Ueno, Kazuko, Darlay, Rebecca, Aiba, Yoshihiro, Hitomi, Yuki, Kawashima, Minae, Nishida, Nao, Khor, Seik-Soon, Gervais, Olivier, Kawai, Yosuke, Nagasaki, Masao, Tokunaga, Katsushi, Tang, Ruqi, Shi, Yongyong, Li, Zhiqiang, Juran, Brian D., Atkinson, Elizabeth J., Gerussi, Alessio, Carbone, Marco, Asselta, Rosanna, Cheung, Angela, de Andrade, Mariza, Baras, Aris, Horowitz, Julie, Ferreira, Manuel A.R., Sun, Dylan, Jones, David E., Flack, Steven, Spicer, Ann, Mulcahy, Victoria L., Byan, Jinyoung, Han, Younghun, Sandford, Richard N., Lazaridis, Konstantinos N., Amos, Christopher I., Hirschfield, Gideon M., Seldin, Michael F., Invernizzi, Pietro, Siminovitch, Katherine A., Ma, Xiong, Nakamura, Minoru, Mells, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811537/
https://www.ncbi.nlm.nih.gov/pubmed/34033851
http://dx.doi.org/10.1016/j.jhep.2021.04.055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811537/
https://www.ncbi.nlm.nih.gov/pubmed/34033851
http://dx.doi.org/10.1016/j.jhep.2021.04.055

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