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Intratumoral IL-1R1 expression delineates a distinctive molecular subset with therapeutic resistance in patients with gastric cancer
BACKGROUND: With the essential role of interleukin-1 signaling in cancer-related inflammation, IL-1R1, the main receptor for both IL-1α and IL-1β, demonstrated therapeutic potential in several types of cancer, which has been put into clinical trials. However, the expression profile and critical role...
Autores principales: | Zhang, Puran, Gu, Yun, Fang, Hanji, Cao, Yifan, Wang, Jieti, Liu, Hao, Zhang, Heng, Li, He, He, Hongyong, Li, Ruochen, Lin, Chao, Xu, Jiejie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811600/ https://www.ncbi.nlm.nih.gov/pubmed/35110359 http://dx.doi.org/10.1136/jitc-2021-004047 |
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