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Platelets subvert antitumor efficacy of T cell-recruiting bispecific antibodies
T cell-based immunotherapy, for example, with T cell-recruiting bispecific antibody (bsAb), has revolutionized oncological treatment. However, many patients do not respond to treatment, and long-term remissions are still rare. Several tumor immune evasion mechanisms have been reported to counteract...
Autores principales: | Lutz, Martina Svenja, Klimovich, Boris, Maurer, Stefanie, Heitmann, Jonas S, Märklin, Melanie, Zekri, Latifa, Jung, Gundram, Salih, Helmut R, Hinterleitner, Clemens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811601/ https://www.ncbi.nlm.nih.gov/pubmed/35110356 http://dx.doi.org/10.1136/jitc-2021-003655 |
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