ENTREP/FAM189A2 encodes a new ITCH ubiquitin ligase activator that is downregulated in breast cancer

The HECT‐type ubiquitin E3 ligases including ITCH regulate many aspects of cellular function through ubiquitinating various substrates. These ligases are known to be allosterically autoinhibited and to require an activator protein to fully achieve the ubiquitination of their substrates. Here we demo...

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Detalles Bibliográficos
Autores principales: Tsunoda, Takumi, Riku, Miho, Yamada, Norika, Tsuchiya, Hikaru, Tomita, Takuya, Suzuki, Minako, Kizuki, Mari, Inoko, Akihito, Ito, Hideaki, Murotani, Kenta, Murakami, Hideki, Saeki, Yasushi, Kasai, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811627/
https://www.ncbi.nlm.nih.gov/pubmed/34927784
http://dx.doi.org/10.15252/embr.202051182

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