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Physiologically relevant miRNAs in mammalian oocytes are rare and highly abundant

miRNAs, ~22nt small RNAs associated with Argonaute (AGO) proteins, are important negative regulators of gene expression in mammalian cells. However, mammalian maternal miRNAs show negligible repressive activity and the miRNA pathway is dispensable for oocytes and maternal‐to‐zygotic transition. The...

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Detalles Bibliográficos
Autores principales:	Kataruka, Shubhangini, Kinterova, Veronika, Horvat, Filip, Kulmann, Marcos Iuri Roos, Kanka, Jiri, Svoboda, Petr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811628/ https://www.ncbi.nlm.nih.gov/pubmed/34866300 http://dx.doi.org/10.15252/embr.202153514

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