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Tet enzymes are essential for early embryogenesis and completion of embryonic genome activation
Mammalian development begins in transcriptional silence followed by a period of widespread activation of thousands of genes. DNA methylation reprogramming is integral to embryogenesis and linked to Tet enzymes, but their function in early development is not well understood. Here, we generate combine...
Autores principales: | Arand, Julia, Chiang, H Rosaria, Martin, David, Snyder, Michael P, Sage, Julien, Reijo Pera, Renee A, Wossidlo, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811641/ https://www.ncbi.nlm.nih.gov/pubmed/34866320 http://dx.doi.org/10.15252/embr.202153968 |
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