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Tet enzymes are essential for early embryogenesis and completion of embryonic genome activation

Mammalian development begins in transcriptional silence followed by a period of widespread activation of thousands of genes. DNA methylation reprogramming is integral to embryogenesis and linked to Tet enzymes, but their function in early development is not well understood. Here, we generate combine...

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Detalles Bibliográficos
Autores principales: Arand, Julia, Chiang, H Rosaria, Martin, David, Snyder, Michael P, Sage, Julien, Reijo Pera, Renee A, Wossidlo, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811641/
https://www.ncbi.nlm.nih.gov/pubmed/34866320
http://dx.doi.org/10.15252/embr.202153968

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