Cargando…

Machine Learning for Cardiovascular Outcomes From Wearable Data: Systematic Review From a Technology Readiness Level Point of View

BACKGROUND: Wearable technology has the potential to improve cardiovascular health monitoring by using machine learning. Such technology enables remote health monitoring and allows for the diagnosis and prevention of cardiovascular diseases. In addition to the detection of cardiovascular disease, it...

Descripción completa

Detalles Bibliográficos
Autores principales: Naseri Jahfari, Arman, Tax, David, Reinders, Marcel, van der Bilt, Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JMIR Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811688/
https://www.ncbi.nlm.nih.gov/pubmed/35044316
http://dx.doi.org/10.2196/29434
_version_ 1784644487287406592
author Naseri Jahfari, Arman
Tax, David
Reinders, Marcel
van der Bilt, Ivo
author_facet Naseri Jahfari, Arman
Tax, David
Reinders, Marcel
van der Bilt, Ivo
author_sort Naseri Jahfari, Arman
collection PubMed
description BACKGROUND: Wearable technology has the potential to improve cardiovascular health monitoring by using machine learning. Such technology enables remote health monitoring and allows for the diagnosis and prevention of cardiovascular diseases. In addition to the detection of cardiovascular disease, it can exclude this diagnosis in symptomatic patients, thereby preventing unnecessary hospital visits. In addition, early warning systems can aid cardiologists in timely treatment and prevention. OBJECTIVE: This study aims to systematically assess the literature on detecting and predicting outcomes of patients with cardiovascular diseases by using machine learning with data obtained from wearables to gain insights into the current state, challenges, and limitations of this technology. METHODS: We searched PubMed, Scopus, and IEEE Xplore on September 26, 2020, with no restrictions on the publication date and by using keywords such as “wearables,” “machine learning,” and “cardiovascular disease.” Methodologies were categorized and analyzed according to machine learning–based technology readiness levels (TRLs), which score studies on their potential to be deployed in an operational setting from 1 to 9 (most ready). RESULTS: After the removal of duplicates, application of exclusion criteria, and full-text screening, 55 eligible studies were included in the analysis, covering a variety of cardiovascular diseases. We assessed the quality of the included studies and found that none of the studies were integrated into a health care system (TRL<6), prospective phase 2 and phase 3 trials were absent (TRL<7 and 8), and group cross-validation was rarely used. These issues limited these studies’ ability to demonstrate the effectiveness of their methodologies. Furthermore, there seemed to be no agreement on the sample size needed to train these studies’ models, the size of the observation window used to make predictions, how long participants should be observed, and the type of machine learning model that is suitable for predicting cardiovascular outcomes. CONCLUSIONS: Although current studies show the potential of wearables to monitor cardiovascular events, their deployment as a diagnostic or prognostic cardiovascular clinical tool is hampered by the lack of a realistic data set and proper systematic and prospective evaluation.
format Online
Article
Text
id pubmed-8811688
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher JMIR Publications
record_format MEDLINE/PubMed
spelling pubmed-88116882022-02-04 Machine Learning for Cardiovascular Outcomes From Wearable Data: Systematic Review From a Technology Readiness Level Point of View Naseri Jahfari, Arman Tax, David Reinders, Marcel van der Bilt, Ivo JMIR Med Inform Review BACKGROUND: Wearable technology has the potential to improve cardiovascular health monitoring by using machine learning. Such technology enables remote health monitoring and allows for the diagnosis and prevention of cardiovascular diseases. In addition to the detection of cardiovascular disease, it can exclude this diagnosis in symptomatic patients, thereby preventing unnecessary hospital visits. In addition, early warning systems can aid cardiologists in timely treatment and prevention. OBJECTIVE: This study aims to systematically assess the literature on detecting and predicting outcomes of patients with cardiovascular diseases by using machine learning with data obtained from wearables to gain insights into the current state, challenges, and limitations of this technology. METHODS: We searched PubMed, Scopus, and IEEE Xplore on September 26, 2020, with no restrictions on the publication date and by using keywords such as “wearables,” “machine learning,” and “cardiovascular disease.” Methodologies were categorized and analyzed according to machine learning–based technology readiness levels (TRLs), which score studies on their potential to be deployed in an operational setting from 1 to 9 (most ready). RESULTS: After the removal of duplicates, application of exclusion criteria, and full-text screening, 55 eligible studies were included in the analysis, covering a variety of cardiovascular diseases. We assessed the quality of the included studies and found that none of the studies were integrated into a health care system (TRL<6), prospective phase 2 and phase 3 trials were absent (TRL<7 and 8), and group cross-validation was rarely used. These issues limited these studies’ ability to demonstrate the effectiveness of their methodologies. Furthermore, there seemed to be no agreement on the sample size needed to train these studies’ models, the size of the observation window used to make predictions, how long participants should be observed, and the type of machine learning model that is suitable for predicting cardiovascular outcomes. CONCLUSIONS: Although current studies show the potential of wearables to monitor cardiovascular events, their deployment as a diagnostic or prognostic cardiovascular clinical tool is hampered by the lack of a realistic data set and proper systematic and prospective evaluation. JMIR Publications 2022-01-19 /pmc/articles/PMC8811688/ /pubmed/35044316 http://dx.doi.org/10.2196/29434 Text en ©Arman Naseri Jahfari, David Tax, Marcel Reinders, Ivo van der Bilt. Originally published in JMIR Medical Informatics (https://medinform.jmir.org), 19.01.2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work, first published in JMIR Medical Informatics, is properly cited. The complete bibliographic information, a link to the original publication on https://medinform.jmir.org/, as well as this copyright and license information must be included.
spellingShingle Review
Naseri Jahfari, Arman
Tax, David
Reinders, Marcel
van der Bilt, Ivo
Machine Learning for Cardiovascular Outcomes From Wearable Data: Systematic Review From a Technology Readiness Level Point of View
title Machine Learning for Cardiovascular Outcomes From Wearable Data: Systematic Review From a Technology Readiness Level Point of View
title_full Machine Learning for Cardiovascular Outcomes From Wearable Data: Systematic Review From a Technology Readiness Level Point of View
title_fullStr Machine Learning for Cardiovascular Outcomes From Wearable Data: Systematic Review From a Technology Readiness Level Point of View
title_full_unstemmed Machine Learning for Cardiovascular Outcomes From Wearable Data: Systematic Review From a Technology Readiness Level Point of View
title_short Machine Learning for Cardiovascular Outcomes From Wearable Data: Systematic Review From a Technology Readiness Level Point of View
title_sort machine learning for cardiovascular outcomes from wearable data: systematic review from a technology readiness level point of view
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811688/
https://www.ncbi.nlm.nih.gov/pubmed/35044316
http://dx.doi.org/10.2196/29434
work_keys_str_mv AT naserijahfariarman machinelearningforcardiovascularoutcomesfromwearabledatasystematicreviewfromatechnologyreadinesslevelpointofview
AT taxdavid machinelearningforcardiovascularoutcomesfromwearabledatasystematicreviewfromatechnologyreadinesslevelpointofview
AT reindersmarcel machinelearningforcardiovascularoutcomesfromwearabledatasystematicreviewfromatechnologyreadinesslevelpointofview
AT vanderbiltivo machinelearningforcardiovascularoutcomesfromwearabledatasystematicreviewfromatechnologyreadinesslevelpointofview