Colchicine for COVID-19: targeting NLRP3 inflammasome to blunt hyperinflammation

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is capable of inducing the activation of NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome, a macromolecular structure sensing the danger and amplifying the inflammatory response. The main product proce...

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Detalles Bibliográficos
Autores principales: Bonaventura, Aldo, Vecchié, Alessandra, Dagna, Lorenzo, Tangianu, Flavio, Abbate, Antonio, Dentali, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811745/
https://www.ncbi.nlm.nih.gov/pubmed/35113170
http://dx.doi.org/10.1007/s00011-022-01540-y

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