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Effects of the IDH1 R132H Mutation on the Energy Metabolism: A Comparison between Tissue and Corresponding Primary Glioma Cell Cultures

[Image: see text] The R132H mutation in the metabolic enzyme isocitrate dehydrogenase 1 (IDH1) is the most important prognostic factor for the survival of glioma patients. Subsequent studies led to the discovery of a panel of enzymes mainly involved in glutamate anaplerosis and aerobic glycolysis th...

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Detalles Bibliográficos
Autores principales:	Dekker, Lennard J. M., Verheul, Cassandra, Wensveen, Nicky, Leenders, William, Lamfers, Martine L. M., Leenstra, Sieger, Luider, Theo M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811756/ https://www.ncbi.nlm.nih.gov/pubmed/35128264 http://dx.doi.org/10.1021/acsomega.1c06121

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