Together is Better: mRNA Co‐Encapsulation in Lipoplexes is Required to Obtain Ratiometric Co‐Delivery and Protein Expression on the Single Cell Level

Liposomes can efficiently deliver messenger RNA (mRNA) into cells. When mRNA cocktails encoding different proteins are needed, a considerable challenge is to efficiently deliver all mRNAs into the cytosol of each individual cell. In this work, two methods are explored to co‐deliver varying ratiometr...

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Detalles Bibliográficos
Autores principales: Zhang, Heyang, Bussmann, Jeroen, Huhnke, Florian H., Devoldere, Joke, Minnaert, An‐Katrien, Jiskoot, Wim, Serwane, Friedhelm, Spatz, Joachim, Röding, Magnus, De Smedt, Stefaan C., Braeckmans, Kevin, Remaut, Katrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811815/
https://www.ncbi.nlm.nih.gov/pubmed/34913603
http://dx.doi.org/10.1002/advs.202102072

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