Cargando…

Oat Plant Amyloids for Sustainable Functional Materials

Amyloid functional materials from amyloid fibril building blocks, produced in vitro from amyloidogenic natural proteins or synthetic peptides, show diverse functionalities ranging from environmental science and biomedicine, to nanotechnology and biomaterials. However, sustainable and affordable sour...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Jiangtao, Li, Ting, Peydayesh, Mohammad, Usuelli, Mattia, Lutz‐Bueno, Viviane, Teng, Jie, Wang, Li, Mezzenga, Raffaele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811842/
https://www.ncbi.nlm.nih.gov/pubmed/34931493
http://dx.doi.org/10.1002/advs.202104445
_version_ 1784644518198378496
author Zhou, Jiangtao
Li, Ting
Peydayesh, Mohammad
Usuelli, Mattia
Lutz‐Bueno, Viviane
Teng, Jie
Wang, Li
Mezzenga, Raffaele
author_facet Zhou, Jiangtao
Li, Ting
Peydayesh, Mohammad
Usuelli, Mattia
Lutz‐Bueno, Viviane
Teng, Jie
Wang, Li
Mezzenga, Raffaele
author_sort Zhou, Jiangtao
collection PubMed
description Amyloid functional materials from amyloid fibril building blocks, produced in vitro from amyloidogenic natural proteins or synthetic peptides, show diverse functionalities ranging from environmental science and biomedicine, to nanotechnology and biomaterials. However, sustainable and affordable sources of amyloidogenic proteins remain the bottleneck for large‐scale applications, and to date, interest remains essentially limited to fundamental studies. Plant‐derived proteins would be an ideal source due to their natural abundance and low environmental impact. Hereby oat globulin, the primary protein of oat plant (Avena sativa), is utilized to yield high‐quality amyloid fibrils and functional materials based thereof. These fibrils show a rich multistranded ribbon‐like polymorphism and a fibrillization process with both irreversible and reversible pathways. The authors furthermore fabricate oat‐amyloid aerogels, films, and membranes for possible use in water purification, sensors, and patterned electrodes. The sustainability footprint of oat‐amyloids against other protein sources is demonstrated, anticipating an environmentally‐efficient platform for advanced materials and technologies.
format Online
Article
Text
id pubmed-8811842
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-88118422022-02-08 Oat Plant Amyloids for Sustainable Functional Materials Zhou, Jiangtao Li, Ting Peydayesh, Mohammad Usuelli, Mattia Lutz‐Bueno, Viviane Teng, Jie Wang, Li Mezzenga, Raffaele Adv Sci (Weinh) Research Articles Amyloid functional materials from amyloid fibril building blocks, produced in vitro from amyloidogenic natural proteins or synthetic peptides, show diverse functionalities ranging from environmental science and biomedicine, to nanotechnology and biomaterials. However, sustainable and affordable sources of amyloidogenic proteins remain the bottleneck for large‐scale applications, and to date, interest remains essentially limited to fundamental studies. Plant‐derived proteins would be an ideal source due to their natural abundance and low environmental impact. Hereby oat globulin, the primary protein of oat plant (Avena sativa), is utilized to yield high‐quality amyloid fibrils and functional materials based thereof. These fibrils show a rich multistranded ribbon‐like polymorphism and a fibrillization process with both irreversible and reversible pathways. The authors furthermore fabricate oat‐amyloid aerogels, films, and membranes for possible use in water purification, sensors, and patterned electrodes. The sustainability footprint of oat‐amyloids against other protein sources is demonstrated, anticipating an environmentally‐efficient platform for advanced materials and technologies. John Wiley and Sons Inc. 2021-12-20 /pmc/articles/PMC8811842/ /pubmed/34931493 http://dx.doi.org/10.1002/advs.202104445 Text en © 2021 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Zhou, Jiangtao
Li, Ting
Peydayesh, Mohammad
Usuelli, Mattia
Lutz‐Bueno, Viviane
Teng, Jie
Wang, Li
Mezzenga, Raffaele
Oat Plant Amyloids for Sustainable Functional Materials
title Oat Plant Amyloids for Sustainable Functional Materials
title_full Oat Plant Amyloids for Sustainable Functional Materials
title_fullStr Oat Plant Amyloids for Sustainable Functional Materials
title_full_unstemmed Oat Plant Amyloids for Sustainable Functional Materials
title_short Oat Plant Amyloids for Sustainable Functional Materials
title_sort oat plant amyloids for sustainable functional materials
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811842/
https://www.ncbi.nlm.nih.gov/pubmed/34931493
http://dx.doi.org/10.1002/advs.202104445
work_keys_str_mv AT zhoujiangtao oatplantamyloidsforsustainablefunctionalmaterials
AT liting oatplantamyloidsforsustainablefunctionalmaterials
AT peydayeshmohammad oatplantamyloidsforsustainablefunctionalmaterials
AT usuellimattia oatplantamyloidsforsustainablefunctionalmaterials
AT lutzbuenoviviane oatplantamyloidsforsustainablefunctionalmaterials
AT tengjie oatplantamyloidsforsustainablefunctionalmaterials
AT wangli oatplantamyloidsforsustainablefunctionalmaterials
AT mezzengaraffaele oatplantamyloidsforsustainablefunctionalmaterials