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Biochemical and Structural Characterization of Human Core Elongator and Its Subassemblies

[Image: see text] Conserved from yeast to humans and composed of six core subunits (Elp1–Elp6), Elongator is a multiprotein complex that catalyzes the modification of the anticodon loop of transfer RNAs (tRNAs) and in turn regulates messenger RNA decoding efficiency. Previous studies showed that yea...

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Detalles Bibliográficos
Autores principales: Dalwadi, Udit, Mannar, Dhiraj, Zierhut, Felix, Yip, Calvin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811885/
https://www.ncbi.nlm.nih.gov/pubmed/35128251
http://dx.doi.org/10.1021/acsomega.1c05719