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A Novel 2-Carbon-Linked Dimeric Artemisinin With Potent Antileukemic Activity and Favorable Pharmacology

Acute myeloid leukemia (AML) remains a devastating disease, with low cure rates despite intensive standard chemotherapy regimens. In the past decade, targeted antileukemic drugs have emerged from research efforts. Nevertheless, targeted therapies are often effective for only a subset of patients who...

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Detalles Bibliográficos
Autores principales: Kagan, Amanda B., Moses, Blake S., Mott, Bryan T., Rai, Ganesha, Anders, Nicole M., Rudek, Michelle A., Civin, Curt I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811960/
https://www.ncbi.nlm.nih.gov/pubmed/35127495
http://dx.doi.org/10.3389/fonc.2021.790037