Machine learning approaches to optimize small-molecule inhibitors for RNA targeting

In the era of data science, data-driven algorithms have emerged as powerful platforms that can consolidate bioisosteric rules for preferential modifications on small molecules with a common molecular scaffold. Here we present complementary data-driven algorithms to minimize the search in chemical sp...

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Detalles Bibliográficos
Autores principales: Grimberg, Hadar, Tiwari, Vinay S., Tam, Benjamin, Gur-Arie, Lihi, Gingold, Daniela, Polachek, Lea, Akabayov, Barak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811966/
https://www.ncbi.nlm.nih.gov/pubmed/35109921
http://dx.doi.org/10.1186/s13321-022-00583-x

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