IKK-mediated CYLD phosphorylation and cellular redox activity

Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms that will be effective in the pathogen...

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Autor principal: Erol, Adnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811971/
https://www.ncbi.nlm.nih.gov/pubmed/35109788
http://dx.doi.org/10.1186/s10020-022-00439-y
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author Erol, Adnan
author_facet Erol, Adnan
author_sort Erol, Adnan
collection PubMed
description Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms that will be effective in the pathogenesis require clarification.
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spelling pubmed-88119712022-02-03 IKK-mediated CYLD phosphorylation and cellular redox activity Erol, Adnan Mol Med Letter to the Editor Oxidative stress is important in the development of obesity-related nephropathy (ORN). A causal relationship between IKK and ORN via CYLD-mediated inhibition of NRF2 has been described. However, contradictory explanations about the functioning of the mechanisms that will be effective in the pathogenesis require clarification. BioMed Central 2022-02-02 /pmc/articles/PMC8811971/ /pubmed/35109788 http://dx.doi.org/10.1186/s10020-022-00439-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Letter to the Editor
Erol, Adnan
IKK-mediated CYLD phosphorylation and cellular redox activity
title IKK-mediated CYLD phosphorylation and cellular redox activity
title_full IKK-mediated CYLD phosphorylation and cellular redox activity
title_fullStr IKK-mediated CYLD phosphorylation and cellular redox activity
title_full_unstemmed IKK-mediated CYLD phosphorylation and cellular redox activity
title_short IKK-mediated CYLD phosphorylation and cellular redox activity
title_sort ikk-mediated cyld phosphorylation and cellular redox activity
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811971/
https://www.ncbi.nlm.nih.gov/pubmed/35109788
http://dx.doi.org/10.1186/s10020-022-00439-y
work_keys_str_mv AT eroladnan ikkmediatedcyldphosphorylationandcellularredoxactivity

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