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MiR-138-5p targets RUNX2 to inhibit osteogenic differentiation of aortic valve interstitial cells via Wnt/β-catenin signaling pathway

BACKGROUND: Human aortic valve interstitial cells (hAVICs) are a key factor in the pathogenesis of calcific aortic valve disease (CAVD). This research examines the role and mechanism of microRNA miR-138-5p in osteogenic differentiation of hAVICs. METHODS: RT-qPCR analysis was applied for detecting m...

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Detalles Bibliográficos
Autores principales:	Yan, Fei, Huo, Qiang, Zhang, Weimin, Wu, Tingting, Dilimulati, Daniyaer, Shi, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8811996/ https://www.ncbi.nlm.nih.gov/pubmed/35109802 http://dx.doi.org/10.1186/s12872-022-02471-6

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