Angiogenic and molecular diversity determine hepatic melanoma metastasis and response to anti-angiogenic treatment

BACKGROUND: Cutaneous melanoma exhibits heterogeneous metastatic patterns and prognosis. In this regard, liver metastasis, which is detected in ~ 10–20% of stage 4 patients, came to the fore of melanoma research, as it recently evolved as decisive indicator of treatment resistance to immune checkpoi...

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Detalles Bibliográficos
Autores principales: Wohlfeil, Sebastian A., Häfele, Verena, Dietsch, Bianca, Weller, Céline, Sticht, Carsten, Jauch, Anna Sophia, Winkler, Manuel, Schmid, Christian David, Irkens, Anna Lena, Olsavszky, Ana, Schledzewski, Kai, Reiners-Koch, Philipp-Sebastian, Goerdt, Sergij, Géraud, Cyrill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812268/
https://www.ncbi.nlm.nih.gov/pubmed/35109875
http://dx.doi.org/10.1186/s12967-022-03255-4

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