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Epigenetic Regulation of F2RL3 Associates With Myocardial Infarction and Platelet Function

DNA hypomethylation at the F2RL3 (F2R like thrombin or trypsin receptor 3) locus has been associated with both smoking and atherosclerotic cardiovascular disease; whether these smoking-related associations form a pathway to disease is unknown. F2RL3 encodes protease-activated receptor 4, a potent th...

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Detalles Bibliográficos
Autores principales:	Corbin, Laura J., White, Stephen J., Taylor, Amy E., Williams, Christopher M., Taylor, Kurt, van den Bosch, Marion T., Teasdale, Jack E., Jones, Matthew, Bond, Mark, Harper, Matthew T., Falk, Louise, Groom, Alix, Hazell, Georgina G.J., Paternoster, Lavinia, Munafò, Marcus R., Nordestgaard, Børge G., Tybjærg-Hansen, Anne, Bojesen, Stig E., Relton, Caroline, Min, Josine L., Davey Smith, George, Mumford, Andrew D., Poole, Alastair W., Timpson, Nicholas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812435/ https://www.ncbi.nlm.nih.gov/pubmed/35012325 http://dx.doi.org/10.1161/CIRCRESAHA.121.318836

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