Vitamin C Intake and Cancers: An Umbrella Review

Based on the existing systematic reviews and meta-analyses, we conducted this umbrella review aiming at evaluating the quality of evidence, validity and biases of the relationship between vitamin C (VC) intake and incidence and outcomes of multiple cancers. We identified 22 cancer outcomes within 3,...

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Detalles Bibliográficos
Autores principales: Chen, Zeyu, Huang, Yin, Cao, Dehong, Qiu, Shi, Chen, Bo, Li, Jin, Bao, Yige, Wei, Qiang, Han, Ping, Liu, Liangren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812486/
https://www.ncbi.nlm.nih.gov/pubmed/35127793
http://dx.doi.org/10.3389/fnut.2021.812394
Descripción
Sumario:Based on the existing systematic reviews and meta-analyses, we conducted this umbrella review aiming at evaluating the quality of evidence, validity and biases of the relationship between vitamin C (VC) intake and incidence and outcomes of multiple cancers. We identified 22 cancer outcomes within 3,562 articles. VC consumption was associated with lower incidence of bladder cancer, breast cancer, cervical tumors, endometrial cancer, esophageal cancer, gastric cancer, glioma, lung cancer, pancreatic cancer, prostate cancer, renal cell cancer, and total cancer occurrence. VC intake was also related to decreased risk of breast cancer prognosis (recurrence, cancer-specific mortality, and all-cause mortality).

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