Vitamin C Intake and Cancers: An Umbrella Review

Based on the existing systematic reviews and meta-analyses, we conducted this umbrella review aiming at evaluating the quality of evidence, validity and biases of the relationship between vitamin C (VC) intake and incidence and outcomes of multiple cancers. We identified 22 cancer outcomes within 3,...

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Autores principales: Chen, Zeyu, Huang, Yin, Cao, Dehong, Qiu, Shi, Chen, Bo, Li, Jin, Bao, Yige, Wei, Qiang, Han, Ping, Liu, Liangren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Nutrition
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812486/
https://www.ncbi.nlm.nih.gov/pubmed/35127793
http://dx.doi.org/10.3389/fnut.2021.812394
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author Chen, Zeyu
Huang, Yin
Cao, Dehong
Qiu, Shi
Chen, Bo
Li, Jin
Bao, Yige
Wei, Qiang
Han, Ping
Liu, Liangren
author_facet Chen, Zeyu
Huang, Yin
Cao, Dehong
Qiu, Shi
Chen, Bo
Li, Jin
Bao, Yige
Wei, Qiang
Han, Ping
Liu, Liangren
author_sort Chen, Zeyu
collection PubMed
description Based on the existing systematic reviews and meta-analyses, we conducted this umbrella review aiming at evaluating the quality of evidence, validity and biases of the relationship between vitamin C (VC) intake and incidence and outcomes of multiple cancers. We identified 22 cancer outcomes within 3,562 articles. VC consumption was associated with lower incidence of bladder cancer, breast cancer, cervical tumors, endometrial cancer, esophageal cancer, gastric cancer, glioma, lung cancer, pancreatic cancer, prostate cancer, renal cell cancer, and total cancer occurrence. VC intake was also related to decreased risk of breast cancer prognosis (recurrence, cancer-specific mortality, and all-cause mortality).
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spelling pubmed-88124862022-02-04 Vitamin C Intake and Cancers: An Umbrella Review Chen, Zeyu Huang, Yin Cao, Dehong Qiu, Shi Chen, Bo Li, Jin Bao, Yige Wei, Qiang Han, Ping Liu, Liangren Front Nutr Nutrition Based on the existing systematic reviews and meta-analyses, we conducted this umbrella review aiming at evaluating the quality of evidence, validity and biases of the relationship between vitamin C (VC) intake and incidence and outcomes of multiple cancers. We identified 22 cancer outcomes within 3,562 articles. VC consumption was associated with lower incidence of bladder cancer, breast cancer, cervical tumors, endometrial cancer, esophageal cancer, gastric cancer, glioma, lung cancer, pancreatic cancer, prostate cancer, renal cell cancer, and total cancer occurrence. VC intake was also related to decreased risk of breast cancer prognosis (recurrence, cancer-specific mortality, and all-cause mortality). Frontiers Media S.A. 2022-01-20 /pmc/articles/PMC8812486/ /pubmed/35127793 http://dx.doi.org/10.3389/fnut.2021.812394 Text en Copyright © 2022 Chen, Huang, Cao, Qiu, Chen, Li, Bao, Wei, Han and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Chen, Zeyu
Huang, Yin
Cao, Dehong
Qiu, Shi
Chen, Bo
Li, Jin
Bao, Yige
Wei, Qiang
Han, Ping
Liu, Liangren
Vitamin C Intake and Cancers: An Umbrella Review
title Vitamin C Intake and Cancers: An Umbrella Review
title_full Vitamin C Intake and Cancers: An Umbrella Review
title_fullStr Vitamin C Intake and Cancers: An Umbrella Review
title_full_unstemmed Vitamin C Intake and Cancers: An Umbrella Review
title_short Vitamin C Intake and Cancers: An Umbrella Review
title_sort vitamin c intake and cancers: an umbrella review
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812486/
https://www.ncbi.nlm.nih.gov/pubmed/35127793
http://dx.doi.org/10.3389/fnut.2021.812394
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