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Sirt6 regulates lifespan in Drosophila melanogaster

Sirt6 is a multifunctional enzyme that regulates diverse cellular processes such as metabolism, DNA repair, and aging. Overexpressing Sirt6 extends lifespan in mice, but the underlying cellular mechanisms are unclear. Drosophila melanogaster are an excellent model to study genetic regulation of life...

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Detalles Bibliográficos
Autores principales:	Taylor, Jackson R., Wood, Jason G., Mizerak, Evan, Hinthorn, Samuel, Liu, Julianna, Finn, Matthew, Gordon, Sarah, Zingas, Louis, Chang, Chengyi, Klein, Mark A., Denu, John M., Gorbunova, Vera, Seluanov, Andrei, Boeke, Jef D., Sedivy, John M., Helfand, Stephen L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812521/ https://www.ncbi.nlm.nih.gov/pubmed/35091469 http://dx.doi.org/10.1073/pnas.2111176119

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