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Ecdysone exerts biphasic control of regenerative signaling, coordinating the completion of regeneration with developmental progression

In Drosophila melanogaster, loss of regenerative capacity in wing imaginal discs coincides with an increase in systemic levels of the steroid hormone ecdysone, a key coordinator of their developmental progression. Regenerating discs release the relaxin hormone Dilp8 (Drosophila insulin-like peptide...

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Detalles Bibliográficos
Autores principales: Karanja, Faith, Sahu, Subhshri, Weintraub, Sara, Bhandari, Rajan, Jaszczak, Rebecca, Sitt, Jason, Halme, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812538/
https://www.ncbi.nlm.nih.gov/pubmed/35086929
http://dx.doi.org/10.1073/pnas.2115017119