LCDR regulates the integrity of lysosomal membrane by hnRNP K–stabilized LAPTM5 transcript and promotes cell survival

Lysosome plays important roles in cellular homeostasis, and its dysregulation contributes to tumor growth and survival. However, the understanding of regulation and the underlying mechanism of lysosome in cancer survival is incomplete. Here, we reveal a role for a histone acetylation–regulated long...

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Detalles Bibliográficos
Autores principales: Yang, Xiwang, Wen, Ya, Liu, Shaomin, Duan, Liqiang, Liu, Tongfeng, Tong, Zhou, Wang, Zhuo, Gu, Yinmin, Xi, Yibo, Wang, Xiaodong, Luo, Dingsan, Zhang, Ruobing, Liu, Yajuan, Wang, Yang, Cheng, Tianyou, Jiang, Siyuan, Zhu, Xiaofeng, Yang, Xiaohui, Pan, Yongbo, Cheng, Shuwen, Ye, Qinong, Chen, Jinfei, Xu, Xiaoding, Gao, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812561/
https://www.ncbi.nlm.nih.gov/pubmed/35091468
http://dx.doi.org/10.1073/pnas.2110428119

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