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Colonic Leucine-Rich Repeat Kinase 2 Expression Is Increased and Associated With Disease Severity in Patients With Parkinson’s Disease

BACKGROUND: Mutations in leucine-rich repeat kinase 2 (LRRK2) comprise a common genetic risk factor for Parkinson’s disease (PD) and inflammatory bowel disease (IBD). We investigated the expression of LRRK2 in colonic biopsies obtained from a cohort of PD patients and healthy controls. METHODS: A co...

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Detalles Bibliográficos
Autores principales:	Liao, Peng-Hsiang, Chiang, Han-Lin, Shun, Chia-Tung, Hang, Jen-Fan, Chiu, Han-Mo, Wu, Ming-Shiang, Lin, Chin-Hsien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812574/ https://www.ncbi.nlm.nih.gov/pubmed/35126095 http://dx.doi.org/10.3389/fnagi.2021.819373

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