Synthetic lipoprotein as nano-material vehicle in the targeted drug delivery

High-density lipoprotein (HDL) and low-density lipoprotein (LDL), as human endogenous lipoprotein particles, have low toxicity, high selectivity, and good safety. They can avoid the recognition and clearance of human reticuloendothelial system. These synthetic lipoproteins (sLPs) have been attracted...

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Detalles Bibliográficos
Autores principales: Zhang, Xueqin, Huang, Gangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812580/
https://www.ncbi.nlm.nih.gov/pubmed/29069931
http://dx.doi.org/10.1080/10717544.2017.1384518
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author Zhang, Xueqin
Huang, Gangliang
author_facet Zhang, Xueqin
Huang, Gangliang
author_sort Zhang, Xueqin
collection PubMed
description High-density lipoprotein (HDL) and low-density lipoprotein (LDL), as human endogenous lipoprotein particles, have low toxicity, high selectivity, and good safety. They can avoid the recognition and clearance of human reticuloendothelial system. These synthetic lipoproteins (sLPs) have been attracted extensive attention as the nanovectors for tumor-targeted drug and gene delivery. Herein, recent advances in the field of anticancer based on these two lipid proteins and recombinant lipoproteins (rLPs) as target delivery vectors were analyzed and discussed.
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spelling pubmed-88125802022-02-04 Synthetic lipoprotein as nano-material vehicle in the targeted drug delivery Zhang, Xueqin Huang, Gangliang Drug Deliv Review High-density lipoprotein (HDL) and low-density lipoprotein (LDL), as human endogenous lipoprotein particles, have low toxicity, high selectivity, and good safety. They can avoid the recognition and clearance of human reticuloendothelial system. These synthetic lipoproteins (sLPs) have been attracted extensive attention as the nanovectors for tumor-targeted drug and gene delivery. Herein, recent advances in the field of anticancer based on these two lipid proteins and recombinant lipoproteins (rLPs) as target delivery vectors were analyzed and discussed. Taylor & Francis 2017-10-25 /pmc/articles/PMC8812580/ /pubmed/29069931 http://dx.doi.org/10.1080/10717544.2017.1384518 Text en © 2017 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Zhang, Xueqin
Huang, Gangliang
Synthetic lipoprotein as nano-material vehicle in the targeted drug delivery
title Synthetic lipoprotein as nano-material vehicle in the targeted drug delivery
title_full Synthetic lipoprotein as nano-material vehicle in the targeted drug delivery
title_fullStr Synthetic lipoprotein as nano-material vehicle in the targeted drug delivery
title_full_unstemmed Synthetic lipoprotein as nano-material vehicle in the targeted drug delivery
title_short Synthetic lipoprotein as nano-material vehicle in the targeted drug delivery
title_sort synthetic lipoprotein as nano-material vehicle in the targeted drug delivery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812580/
https://www.ncbi.nlm.nih.gov/pubmed/29069931
http://dx.doi.org/10.1080/10717544.2017.1384518
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AT huanggangliang syntheticlipoproteinasnanomaterialvehicleinthetargeteddrugdelivery

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