Cargando…

An Insight Into Lyme Prosthetic Joint Infection in Knee Arthroplasty: A Literature Review

Lyme prosthetic joint infection (PJI) is a rare event, but it is imperative to include Lyme disease as a possible cause of PJI in a Lyme-endemic region. The purpose of this article was to review the reported cases of Lyme PJIs in knee arthroplasty and to initiate the development of a treatment strat...

Descripción completa

Detalles Bibliográficos
Autores principales: Ali, Muzaffar, Kamson, Anthony O., Phillips, David S., King, Scott G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812602/
https://www.ncbi.nlm.nih.gov/pubmed/35133991
http://dx.doi.org/10.5435/JAAOSGlobal-D-21-00191
_version_ 1784644689502142464
author Ali, Muzaffar
Kamson, Anthony O.
Phillips, David S.
King, Scott G.
author_facet Ali, Muzaffar
Kamson, Anthony O.
Phillips, David S.
King, Scott G.
author_sort Ali, Muzaffar
collection PubMed
description Lyme prosthetic joint infection (PJI) is a rare event, but it is imperative to include Lyme disease as a possible cause of PJI in a Lyme-endemic region. The purpose of this article was to review the reported cases of Lyme PJIs in knee arthroplasty and to initiate the development of a treatment strategy. We found five cases of Lyme PJI in the literature. All patients lived in the northeastern region of the United States. Four patients were successfully treated with surgical intervention and postoperative antibiotics. One patient was successfully treated with intravenous and oral antibiotics for 6 weeks, without surgical intervention. Synovial fluid Lyme polymerase chain reaction and serological tests were positive in all patients. On follow-up visits, after completion of their treatment, all patients were asymptomatic with a painless functional knee. We recommend considering Lyme disease as a cause of culture-negative PJIs in endemic regions. Additional research is needed to clearly define a treatment algorithm. Based on our literature review, we cannot recommend a single best treatment modality for the treatment of Lyme PJI. However, early irrigation and débridement with administration of postoperative antibiotics may improve early clinical outcomes.
format Online
Article
Text
id pubmed-8812602
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer
record_format MEDLINE/PubMed
spelling pubmed-88126022022-02-18 An Insight Into Lyme Prosthetic Joint Infection in Knee Arthroplasty: A Literature Review Ali, Muzaffar Kamson, Anthony O. Phillips, David S. King, Scott G. J Am Acad Orthop Surg Glob Res Rev Review Article Lyme prosthetic joint infection (PJI) is a rare event, but it is imperative to include Lyme disease as a possible cause of PJI in a Lyme-endemic region. The purpose of this article was to review the reported cases of Lyme PJIs in knee arthroplasty and to initiate the development of a treatment strategy. We found five cases of Lyme PJI in the literature. All patients lived in the northeastern region of the United States. Four patients were successfully treated with surgical intervention and postoperative antibiotics. One patient was successfully treated with intravenous and oral antibiotics for 6 weeks, without surgical intervention. Synovial fluid Lyme polymerase chain reaction and serological tests were positive in all patients. On follow-up visits, after completion of their treatment, all patients were asymptomatic with a painless functional knee. We recommend considering Lyme disease as a cause of culture-negative PJIs in endemic regions. Additional research is needed to clearly define a treatment algorithm. Based on our literature review, we cannot recommend a single best treatment modality for the treatment of Lyme PJI. However, early irrigation and débridement with administration of postoperative antibiotics may improve early clinical outcomes. Wolters Kluwer 2022-02-02 /pmc/articles/PMC8812602/ /pubmed/35133991 http://dx.doi.org/10.5435/JAAOSGlobal-D-21-00191 Text en Copyright © 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Orthopaedic Surgeons. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ali, Muzaffar
Kamson, Anthony O.
Phillips, David S.
King, Scott G.
An Insight Into Lyme Prosthetic Joint Infection in Knee Arthroplasty: A Literature Review
title An Insight Into Lyme Prosthetic Joint Infection in Knee Arthroplasty: A Literature Review
title_full An Insight Into Lyme Prosthetic Joint Infection in Knee Arthroplasty: A Literature Review
title_fullStr An Insight Into Lyme Prosthetic Joint Infection in Knee Arthroplasty: A Literature Review
title_full_unstemmed An Insight Into Lyme Prosthetic Joint Infection in Knee Arthroplasty: A Literature Review
title_short An Insight Into Lyme Prosthetic Joint Infection in Knee Arthroplasty: A Literature Review
title_sort insight into lyme prosthetic joint infection in knee arthroplasty: a literature review
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812602/
https://www.ncbi.nlm.nih.gov/pubmed/35133991
http://dx.doi.org/10.5435/JAAOSGlobal-D-21-00191
work_keys_str_mv AT alimuzaffar aninsightintolymeprostheticjointinfectioninkneearthroplastyaliteraturereview
AT kamsonanthonyo aninsightintolymeprostheticjointinfectioninkneearthroplastyaliteraturereview
AT phillipsdavids aninsightintolymeprostheticjointinfectioninkneearthroplastyaliteraturereview
AT kingscottg aninsightintolymeprostheticjointinfectioninkneearthroplastyaliteraturereview
AT alimuzaffar insightintolymeprostheticjointinfectioninkneearthroplastyaliteraturereview
AT kamsonanthonyo insightintolymeprostheticjointinfectioninkneearthroplastyaliteraturereview
AT phillipsdavids insightintolymeprostheticjointinfectioninkneearthroplastyaliteraturereview
AT kingscottg insightintolymeprostheticjointinfectioninkneearthroplastyaliteraturereview