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Visualizing the features of inflection point shown on a temporal bar graph using the data of COVID-19 pandemic

BACKGROUND: Exponential-like infection growth leading to peaks (denoted by inflection points [IP] or turning points) is usually the hallmark of infectious disease outbreaks, including coronaviruses. To determine the IPs of the novel coronavirus (COVID-19), we applied the item response theory model t...

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Detalles Bibliográficos
Autores principales: Ho, Sam Yu-Chieh, Chien, Tsair-Wei, Shao, Yang, Hsieh, Ju-Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812627/
https://www.ncbi.nlm.nih.gov/pubmed/35119031
http://dx.doi.org/10.1097/MD.0000000000028749
Descripción
Sumario:BACKGROUND: Exponential-like infection growth leading to peaks (denoted by inflection points [IP] or turning points) is usually the hallmark of infectious disease outbreaks, including coronaviruses. To determine the IPs of the novel coronavirus (COVID-19), we applied the item response theory model to detect phase transitions for each country/region and characterize the IP feature on the temporal bar graph (TBG). METHODS: The IP (using the item difficulty parameter to locate) was verified by the differential equation in calculus and interpreted by the TBG with 2 virtual and real empirical data (i.e., from Collatz conjecture and COVID-19 pandemic in 2020). Comparisons of IPs, R(2), and burst strength [BS = ln([Formula: see text]) denoted by the infection number at IP(Nip) and the item slope parameter(a) in item response theory were made for countries/regions and continents on the choropleth map and the forest plot. RESULTS: We found that the evolution of COVID-19 on the TBG makes the data clear and easy to understand, the shorter IP (=53.9) was in China and the longest (=247.3) was in Europe, and the highest R(2) (as the variance explained by the model) was in the US, with a mean R(2) of 0.98. We successfully estimated the IPs for countries/regions on COVID-19 in 2020 and presented them on the TBG. CONCLUSION: Temporal visualization is recommended for researchers in future relevant studies (e.g., the evolution of keywords in a specific discipline) and is not merely limited to the IP search in COVID-19 pandemics as we did in this study.