Discovery of triterpenoids as potent dual inhibitors of pancreatic lipase and human carboxylesterase 1

Pancreatic lipase (PL) is a well-known key target for the prevention and treatment of obesity. Human carboxylesterase 1A (hCES1A) has become an important target for the treatment of hyperlipidaemia. Thus, the discovery of potent dual-target inhibitors based on PL and hCES1A hold great potential for...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Pan, Qiu-Sha, Qian, Xing-Kai, Zhou, Xiang-Lu, Wang, Ya-Jie, He, Rong-Jing, Wang, Le-Tian, Li, Yan-Ran, Huo, Hong, Sun, Cheng-Gong, Sun, Lei, Zou, Li-Wei, Yang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812735/
https://www.ncbi.nlm.nih.gov/pubmed/35100926
http://dx.doi.org/10.1080/14756366.2022.2029855

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