Pharmacological suppression of glycogen synthase kinase-3 reactivates HIV-1 from latency via activating Wnt/β-catenin/TCF1 axis in CD4(+) T cells

HIV-1 latency posts a major obstacle for HIV-1 eradication. Currently, no desirable latency reversing agents (LRAs) have been implicated in the “Shock and Kill” strategy to mobilize the latently infected cells to be susceptible for clearance by immune responses. Identification of key cellular pathwa...

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Detalles Bibliográficos
Autores principales: Wen, Jing, Li, Xin, Zhao, Qing-Xia, Yang, Xiao-Fan, Wu, Meng-Li, Yan, Qihong, Chang, Junbiao, Wang, Haikun, Jin, Xia, Su, Xiao, Deng, Kai, Chen, Ling, Wang, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812804/
https://www.ncbi.nlm.nih.gov/pubmed/34985411
http://dx.doi.org/10.1080/22221751.2022.2026198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812804/
https://www.ncbi.nlm.nih.gov/pubmed/34985411
http://dx.doi.org/10.1080/22221751.2022.2026198

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