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Human NAIP/NLRC4 and NLRP3 inflammasomes detect Salmonella type III secretion system activities to restrict intracellular bacterial replication

Salmonella enterica serovar Typhimurium is a Gram-negative pathogen that uses two distinct type III secretion systems (T3SSs), termed Salmonella pathogenicity island (SPI)-1 and SPI-2, to deliver virulence factors into the host cell. The SPI-1 T3SS enables Salmonella to invade host cells, while the...

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Detalles Bibliográficos
Autores principales:	Naseer, Nawar, Egan, Marisa S., Reyes Ruiz, Valeria M., Scott, William P., Hunter, Emma N., Demissie, Tabitha, Rauch, Isabella, Brodsky, Igor E., Shin, Sunny
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812861/ https://www.ncbi.nlm.nih.gov/pubmed/35073381 http://dx.doi.org/10.1371/journal.ppat.1009718

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