High level SARS-CoV-2 nucleocapsid refolding using mild condition for inclusion bodies solubilization: Application of high pressure at pH 9.0

SARS-CoV-2 Nucleocapsid (N) is the most abundant viral protein expressed in host samples and is an important antigen for diagnosis. N is a 45 kDa protein that does not present disulfide bonds. Intending to avoid non-specific binding of SARS-CoV-2 N to antibodies from patients who previously had diff...

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Detalles Bibliográficos
Autores principales: Chura-Chambi, Rosa Maria, Prieto-da-Silva, Alvaro Rossan de Brandão, Di Lela, Matheus Martins, Oliveira, João Ezequiel, Abreu, Patricia Estima Antonia, Meireles, Luciana Regina, de Andrade Junior, Heitor Franco, Morganti, Ligia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812862/
https://www.ncbi.nlm.nih.gov/pubmed/35113919
http://dx.doi.org/10.1371/journal.pone.0262591

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