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Selected by bioinformatics and molecular docking analysis, Dhea and 2–14,15-Eg are effective against cholangiocarcinoma

OBJECT: To identify novel targets for the diagnosis, treatment and prognosis of cholangiocarcinoma, we screen ideal lead compounds and preclinical drug candidates with MYC inhibitory effect from the ZINC database, and verify the therapeutic effect of Dhea and 2–14,15-Eg on cholangiocarcinoma. METHOD...

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Detalles Bibliográficos
Autores principales:	Qin, Lei, Kuai, Jun, Yang, Fang, Yang, Lu, Sun, Peisheng, Zhang, Lanfang, Li, Guangpeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8812988/ https://www.ncbi.nlm.nih.gov/pubmed/35113866 http://dx.doi.org/10.1371/journal.pone.0260180

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