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Molecular determinants of phase separation for Drosophila DNA replication licensing factors

Liquid–liquid phase separation (LLPS) of intrinsically disordered regions (IDRs) in proteins can drive the formation of membraneless compartments in cells. Phase-separated structures enrich for specific partner proteins and exclude others. Previously, we showed that the IDRs of metazoan DNA replicat...

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Detalles Bibliográficos
Autores principales:	Parker, Matthew W, Kao, Jonchee A, Huang, Alvin, Berger, James M, Botchan, Michael R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2021
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813052/ https://www.ncbi.nlm.nih.gov/pubmed/34951585 http://dx.doi.org/10.7554/eLife.70535

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