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Acetylation-dependent regulation of BRAF oncogenic function

Aberrant BRAF activation, including the BRAF(V600E) mutation, is frequently observed in human cancers. However, it remains largely elusive whether other types of post-translational modification(s) in addition to phosphorylation and ubiquitination-dependent regulation also modulate BRAF kinase activi...

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Detalles Bibliográficos
Autores principales: Dai, Xiangpeng, Zhang, Xiaoling, Yin, Qing, Hu, Jia, Guo, Jianping, Gao, Yang, Snell, Aidan H., Inuzuka, Hiroyuki, Wan, Lixin, Wei, Wenyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813213/
https://www.ncbi.nlm.nih.gov/pubmed/35045286
http://dx.doi.org/10.1016/j.celrep.2021.110250