Cargando…
Cardioprotective Effect of circ_SMG6 Knockdown against Myocardial Ischemia/Reperfusion Injury Correlates with miR-138-5p-Mediated EGR1/TLR4/TRIF Inactivation
Increased neutrophil recruitment represents a hallmark event in myocardial ischemia/reperfusion (I/R) injury due to the ensuing inflammatory response. Circular RNAs (circRNAs) are important regulatory molecules involved in cell physiology and pathology. Herein, we analyzed the role of a novel circRN...
Autores principales: | Huang, Chen, Qu, Yalun, Feng, Fan, Zhang, Hualu, Shu, Liliang, Zhu, Xiaohua, Huang, Gongcheng, Xu, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813281/ https://www.ncbi.nlm.nih.gov/pubmed/35126807 http://dx.doi.org/10.1155/2022/1927260 |
Ejemplares similares
-
Egr2-dependent microRNA-138 is dispensable for peripheral nerve myelination
por: Lin, Hsin-Pin, et al.
Publicado: (2018) -
ZCCHC3 modulates TLR3-mediated signaling by promoting recruitment of TRIF to TLR3
por: Zang, Ru, et al.
Publicado: (2020) -
SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance
por: Llorca-Cardenosa, Marta J., et al.
Publicado: (2022) -
SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity
por: Boehm, Volker, et al.
Publicado: (2021) -
TRIF Is Required for TLR4 Mediated Adjuvant Effects on T Cell Clonal Expansion
por: Gandhapudi, Siva K., et al.
Publicado: (2013)