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Estimating the cost of COVID-19 vaccine deployment and introduction in Ghana using the CVIC tool

BACKGROUND: This study estimated cost of COVID-19 vaccine introduction and deployment in Ghana. METHODS: Using the WHO-UNICEF COVID-19 Vaccine Introduction and deployment Costing (CVIC) tool Ghana’s Ministry of Health Technical Working Group for Health Technology Assessment (TWG-HTA) in collaboratio...

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Autores principales: Nonvignon, Justice, Owusu, Richmond, Asare, Brian, Adjagba, Alex, Aun, Yap Wei, Yeung, Karene Hoi Ting, Azeez, Joycelyn Naa Korkoi, Gyansa-Lutterodt, Martha, Gulbi, Godwin, Amponsa-Achiano, Kwame, Dadzie, Frederick, Armah, George E., Brenzel, Logan, Hutubessy, Raymond, Resch, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813551/
https://www.ncbi.nlm.nih.gov/pubmed/35190206
http://dx.doi.org/10.1016/j.vaccine.2022.01.036
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author Nonvignon, Justice
Owusu, Richmond
Asare, Brian
Adjagba, Alex
Aun, Yap Wei
Yeung, Karene Hoi Ting
Azeez, Joycelyn Naa Korkoi
Gyansa-Lutterodt, Martha
Gulbi, Godwin
Amponsa-Achiano, Kwame
Dadzie, Frederick
Armah, George E.
Brenzel, Logan
Hutubessy, Raymond
Resch, Stephen C.
author_facet Nonvignon, Justice
Owusu, Richmond
Asare, Brian
Adjagba, Alex
Aun, Yap Wei
Yeung, Karene Hoi Ting
Azeez, Joycelyn Naa Korkoi
Gyansa-Lutterodt, Martha
Gulbi, Godwin
Amponsa-Achiano, Kwame
Dadzie, Frederick
Armah, George E.
Brenzel, Logan
Hutubessy, Raymond
Resch, Stephen C.
author_sort Nonvignon, Justice
collection PubMed
description BACKGROUND: This study estimated cost of COVID-19 vaccine introduction and deployment in Ghana. METHODS: Using the WHO-UNICEF COVID-19 Vaccine Introduction and deployment Costing (CVIC) tool Ghana’s Ministry of Health Technical Working Group for Health Technology Assessment (TWG-HTA) in collaboration with School of Public Health, University of Ghana, organized an initial two-day workshop that brought together partners to deliberate and agree on input parameters to populate the CVIC tool. A further 2–3 days validation with the Expanded Program of Immunization (EPI) and other partners to finalize the analysis was done. Three scenarios, with different combinations of vaccine products and delivery modalities, as well as time period were analyzed. The scenarios included AstraZeneca (40%), Johnson & Johnson (J&J) (30%), Moderna, Pfizer, and Sputnik V at 10% each; with primary schedule completed by second half of 2021 (Scenario 1); AstraZeneca (30%), J&J (40%), Moderna, Pfizer, and Sputnik V at 10% each with primary schedule completed by first half of 2022 (Scenario 2); and equal distribution (20%) among AstraZeneca, J&J, Moderna, Pfizer, and Sputnik V with primary schedule completed by second half of 2022 (Scenario 3). RESULTS: The estimated total cost of COVID-19 vaccination ranges between $348.7 and $436.1 million for the target population of 17.5 million. These translate into per person completed primary schedule cost of $20.9–$26.2 and per dose (including vaccine cost) of $10.5–$13.1. Again, per person completed primary schedule excluding vaccine cost was $4.5 and $4.6, thus per dose excluding vaccine also ranged from $2.2 – $2.3. The main cost driver was vaccine doses, including shipping, which accounts for between 78% and 83% of total cost. Further, an estimated 8,437–10,247 vaccinators (non-FTEs) would be required during 2021–2022 to vaccinate using a mix of delivery strategies, accounting for 8–10% of total cost. CONCLUSION: These findings provide the estimates to inform resource mobilization efforts by government and other partners.
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spelling pubmed-88135512022-02-04 Estimating the cost of COVID-19 vaccine deployment and introduction in Ghana using the CVIC tool Nonvignon, Justice Owusu, Richmond Asare, Brian Adjagba, Alex Aun, Yap Wei Yeung, Karene Hoi Ting Azeez, Joycelyn Naa Korkoi Gyansa-Lutterodt, Martha Gulbi, Godwin Amponsa-Achiano, Kwame Dadzie, Frederick Armah, George E. Brenzel, Logan Hutubessy, Raymond Resch, Stephen C. Vaccine Article BACKGROUND: This study estimated cost of COVID-19 vaccine introduction and deployment in Ghana. METHODS: Using the WHO-UNICEF COVID-19 Vaccine Introduction and deployment Costing (CVIC) tool Ghana’s Ministry of Health Technical Working Group for Health Technology Assessment (TWG-HTA) in collaboration with School of Public Health, University of Ghana, organized an initial two-day workshop that brought together partners to deliberate and agree on input parameters to populate the CVIC tool. A further 2–3 days validation with the Expanded Program of Immunization (EPI) and other partners to finalize the analysis was done. Three scenarios, with different combinations of vaccine products and delivery modalities, as well as time period were analyzed. The scenarios included AstraZeneca (40%), Johnson & Johnson (J&J) (30%), Moderna, Pfizer, and Sputnik V at 10% each; with primary schedule completed by second half of 2021 (Scenario 1); AstraZeneca (30%), J&J (40%), Moderna, Pfizer, and Sputnik V at 10% each with primary schedule completed by first half of 2022 (Scenario 2); and equal distribution (20%) among AstraZeneca, J&J, Moderna, Pfizer, and Sputnik V with primary schedule completed by second half of 2022 (Scenario 3). RESULTS: The estimated total cost of COVID-19 vaccination ranges between $348.7 and $436.1 million for the target population of 17.5 million. These translate into per person completed primary schedule cost of $20.9–$26.2 and per dose (including vaccine cost) of $10.5–$13.1. Again, per person completed primary schedule excluding vaccine cost was $4.5 and $4.6, thus per dose excluding vaccine also ranged from $2.2 – $2.3. The main cost driver was vaccine doses, including shipping, which accounts for between 78% and 83% of total cost. Further, an estimated 8,437–10,247 vaccinators (non-FTEs) would be required during 2021–2022 to vaccinate using a mix of delivery strategies, accounting for 8–10% of total cost. CONCLUSION: These findings provide the estimates to inform resource mobilization efforts by government and other partners. Elsevier Science 2022-03-15 /pmc/articles/PMC8813551/ /pubmed/35190206 http://dx.doi.org/10.1016/j.vaccine.2022.01.036 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nonvignon, Justice
Owusu, Richmond
Asare, Brian
Adjagba, Alex
Aun, Yap Wei
Yeung, Karene Hoi Ting
Azeez, Joycelyn Naa Korkoi
Gyansa-Lutterodt, Martha
Gulbi, Godwin
Amponsa-Achiano, Kwame
Dadzie, Frederick
Armah, George E.
Brenzel, Logan
Hutubessy, Raymond
Resch, Stephen C.
Estimating the cost of COVID-19 vaccine deployment and introduction in Ghana using the CVIC tool
title Estimating the cost of COVID-19 vaccine deployment and introduction in Ghana using the CVIC tool
title_full Estimating the cost of COVID-19 vaccine deployment and introduction in Ghana using the CVIC tool
title_fullStr Estimating the cost of COVID-19 vaccine deployment and introduction in Ghana using the CVIC tool
title_full_unstemmed Estimating the cost of COVID-19 vaccine deployment and introduction in Ghana using the CVIC tool
title_short Estimating the cost of COVID-19 vaccine deployment and introduction in Ghana using the CVIC tool
title_sort estimating the cost of covid-19 vaccine deployment and introduction in ghana using the cvic tool
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813551/
https://www.ncbi.nlm.nih.gov/pubmed/35190206
http://dx.doi.org/10.1016/j.vaccine.2022.01.036
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