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Malignant transformation of a dysembryoplastic neuroepithelial tumor presenting with intraventricular hemorrhage()

Dysembryoplastic neuroepithelial tumors (DNTs) are benign brain tumors classified as grade 1 in the 2021 World Health Organization (WHO) classification of central nervous system tumors. DNTs rarely undergo malignant transformation and cause symptomatic intracranial hemorrhage. We report a case of ma...

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Detalles Bibliográficos
Autores principales: Takita, Hirotaka, Shimono, Taro, Uda, Takehiro, Ikota, Hayato, Kawashima, Toshiyuki, Horiuchi, Daisuke, Terayama, Eisaku, Tsukamoto, Taro, Miki, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813558/
https://www.ncbi.nlm.nih.gov/pubmed/35140831
http://dx.doi.org/10.1016/j.radcr.2022.01.014
Descripción
Sumario:Dysembryoplastic neuroepithelial tumors (DNTs) are benign brain tumors classified as grade 1 in the 2021 World Health Organization (WHO) classification of central nervous system tumors. DNTs rarely undergo malignant transformation and cause symptomatic intracranial hemorrhage. We report a case of malignant transformation of DNT presenting with intraventricular hemorrhage and review the literature on malignant transformation of DNTs. An 18-year-old woman with a history of epilepsy presented with a sudden headache and vomiting. Radiological examination revealed a mass lesion in the left parietal lobe and intraventricular hemorrhage. The patient underwent an emergency craniotomy for brain tumor resection. The lesion was pathologically diagnosed as a malignant transformation of DNT. She had been followed up without tumor recurrence for 2 years after surgery.