Identification of novel SARS-CoV-2 RNA dependent RNA polymerase (RdRp) inhibitors: From in silico screening to experimentally validated inhibitory activity

The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 2019 has posed a serious threat to global health and the economy for over two years, prompting the need for development of antiviral inhibitors. Due to its vital role in viral replication, RNA-dependent RNA polymerase (...

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Detalles Bibliográficos
Autores principales: Uengwetwanit, Tanaporn, Chutiwitoonchai, Nopporn, Wichapong, Kanin, Karoonuthaisiri, Nitsara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8813674/
https://www.ncbi.nlm.nih.gov/pubmed/35136534
http://dx.doi.org/10.1016/j.csbj.2022.02.001

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